Lane-Hamilton syndrome: case report and review of the literature
Identifieur interne : 001547 ( Main/Exploration ); précédent : 001546; suivant : 001548Lane-Hamilton syndrome: case report and review of the literature
Auteurs : Guy F. M. Hendrickx [Belgique, Pays-Bas] ; Katia Somers [Pays-Bas] ; Yvan Vandenplas [Belgique]Source :
- European Journal of Pediatrics [ 0340-6199 ] ; 2011-12-01.
English descriptors
Abstract
Abstract: We report a case of a three-and-a-half-year-old boy, who presented with poor general condition, stunted growth, had the presence of nail clubbing, persistent cough and frequent diarrhoea. Persistent iron deficiency anaemia without signs of haemolysis suggested Lane-Hamilton syndrome (LHS) which is or/is an extremely rare combination of idiopathic pulmonary haemosiderosis (IPH) and celiac disease (CD), although both diseases are immunologically mediated and the pathogenetic link between them is not clear. We have now 3 years of follow-up on gluten-free diet (GFD), resulting in a gradual recovery of the abnormal laboratory results in combination with an improving growth. Clinically, he is asymptomatic without any additional treatment. Our case illustrates that CD should be specifically looked for in patients with IPH, especially those in whom the severity of anaemia is disproportionate to the IPH symptoms. Both diseases may benefit from a GFD.
Url:
DOI: 10.1007/s00431-011-1568-5
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002806
- to stream Istex, to step Curation: 002806
- to stream Istex, to step Checkpoint: 000523
- to stream Main, to step Merge: 001549
- to stream Main, to step Curation: 001547
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lane-Hamilton syndrome: case report and review of the literature</title>
<author><name sortKey="Hendrickx, Guy F M" sort="Hendrickx, Guy F M" uniqKey="Hendrickx G" first="Guy F. M." last="Hendrickx">Guy F. M. Hendrickx</name>
</author>
<author><name sortKey="Somers, Katia" sort="Somers, Katia" uniqKey="Somers K" first="Katia" last="Somers">Katia Somers</name>
</author>
<author><name sortKey="Vandenplas, Yvan" sort="Vandenplas, Yvan" uniqKey="Vandenplas Y" first="Yvan" last="Vandenplas">Yvan Vandenplas</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:EA296FE83200D0313755E0E7680CBCB84375585E</idno>
<date when="2011" year="2011">2011</date>
<idno type="doi">10.1007/s00431-011-1568-5</idno>
<idno type="url">https://api.istex.fr/ark:/67375/VQC-86FGPNWN-C/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002806</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002806</idno>
<idno type="wicri:Area/Istex/Curation">002806</idno>
<idno type="wicri:Area/Istex/Checkpoint">000523</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000523</idno>
<idno type="wicri:doubleKey">0340-6199:2011:Hendrickx G:lane:hamilton:syndrome</idno>
<idno type="wicri:Area/Main/Merge">001549</idno>
<idno type="wicri:Area/Main/Curation">001547</idno>
<idno type="wicri:Area/Main/Exploration">001547</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Lane-Hamilton syndrome: case report and review of the literature</title>
<author><name sortKey="Hendrickx, Guy F M" sort="Hendrickx, Guy F M" uniqKey="Hendrickx G" first="Guy F. M." last="Hendrickx">Guy F. M. Hendrickx</name>
<affiliation wicri:level="1"><country xml:lang="fr">Belgique</country>
<wicri:regionArea>UZ kinderziekenhuis Brussel, Laarbeeklaan, 101, 1090, Brussel</wicri:regionArea>
<wicri:noRegion>Brussel</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Paediatrics, Sint Annakliniek, Bogardeind, 2, 5664 EH, Geldrop</wicri:regionArea>
<wicri:noRegion>Geldrop</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">Belgique</country>
</affiliation>
</author>
<author><name sortKey="Somers, Katia" sort="Somers, Katia" uniqKey="Somers K" first="Katia" last="Somers">Katia Somers</name>
<affiliation wicri:level="1"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Laboratorium voor Pathologie, Stichting PAMM, Michelangelolaan, 2, 5623 EJ, Eindhoven</wicri:regionArea>
<wicri:noRegion>Eindhoven</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vandenplas, Yvan" sort="Vandenplas, Yvan" uniqKey="Vandenplas Y" first="Yvan" last="Vandenplas">Yvan Vandenplas</name>
<affiliation wicri:level="1"><country xml:lang="fr">Belgique</country>
<wicri:regionArea>UZ kinderziekenhuis Brussel, Laarbeeklaan, 101, 1090, Brussel</wicri:regionArea>
<wicri:noRegion>Brussel</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">European Journal of Pediatrics</title>
<title level="j" type="abbrev">Eur J Pediatr</title>
<idno type="ISSN">0340-6199</idno>
<idno type="eISSN">1432-1076</idno>
<imprint><publisher>Springer-Verlag</publisher>
<pubPlace>Berlin/Heidelberg</pubPlace>
<date type="published" when="2011-12-01">2011-12-01</date>
<biblScope unit="volume">170</biblScope>
<biblScope unit="issue">12</biblScope>
<biblScope unit="page" from="1597">1597</biblScope>
<biblScope unit="page" to="1602">1602</biblScope>
</imprint>
<idno type="ISSN">0340-6199</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0340-6199</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Celiac disease</term>
<term>Idiopathic pulmonary haemosiderosis</term>
<term>Lane-Hamilton syndrome</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Abstract: We report a case of a three-and-a-half-year-old boy, who presented with poor general condition, stunted growth, had the presence of nail clubbing, persistent cough and frequent diarrhoea. Persistent iron deficiency anaemia without signs of haemolysis suggested Lane-Hamilton syndrome (LHS) which is or/is an extremely rare combination of idiopathic pulmonary haemosiderosis (IPH) and celiac disease (CD), although both diseases are immunologically mediated and the pathogenetic link between them is not clear. We have now 3 years of follow-up on gluten-free diet (GFD), resulting in a gradual recovery of the abnormal laboratory results in combination with an improving growth. Clinically, he is asymptomatic without any additional treatment. Our case illustrates that CD should be specifically looked for in patients with IPH, especially those in whom the severity of anaemia is disproportionate to the IPH symptoms. Both diseases may benefit from a GFD.</div>
</front>
</TEI>
<affiliations><list><country><li>Belgique</li>
<li>Pays-Bas</li>
</country>
</list>
<tree><country name="Belgique"><noRegion><name sortKey="Hendrickx, Guy F M" sort="Hendrickx, Guy F M" uniqKey="Hendrickx G" first="Guy F. M." last="Hendrickx">Guy F. M. Hendrickx</name>
</noRegion>
<name sortKey="Hendrickx, Guy F M" sort="Hendrickx, Guy F M" uniqKey="Hendrickx G" first="Guy F. M." last="Hendrickx">Guy F. M. Hendrickx</name>
<name sortKey="Vandenplas, Yvan" sort="Vandenplas, Yvan" uniqKey="Vandenplas Y" first="Yvan" last="Vandenplas">Yvan Vandenplas</name>
</country>
<country name="Pays-Bas"><noRegion><name sortKey="Hendrickx, Guy F M" sort="Hendrickx, Guy F M" uniqKey="Hendrickx G" first="Guy F. M." last="Hendrickx">Guy F. M. Hendrickx</name>
</noRegion>
<name sortKey="Somers, Katia" sort="Somers, Katia" uniqKey="Somers K" first="Katia" last="Somers">Katia Somers</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001547 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001547 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= ChloroquineV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:EA296FE83200D0313755E0E7680CBCB84375585E |texte= Lane-Hamilton syndrome: case report and review of the literature }}
This area was generated with Dilib version V0.6.33. |